has course role

• BME7979 Advanced Research
• BME7980 Doctoral Research
• BMS4905 Med Sci Senior Res
• BMS6601C Gen Pathol & Immunol
• BMS6602C Sys Pathol/lab Med
• GMS6033 Immunity Hlth & Disea
• GMS6090 Research In Med Sci
• GMS6140 Principles Immunology
• GMS6382 Adv Topics Immunology
• GMS7979 Advanced Research
• GMS7980 Doctoral Research
• IDH4917 Undergrad Research
• MCB4905 Undergrad Research
• ZOO4905 Indiv Studies Zoology

selected publications

• academic article

  • Anti-Thymocyte Globulin (Atg) Differentially Depletes Naive and Memory T Cells and Permits Memory-Type Regulatory T Cells in Nonobese Diabetic Mice.  Bmc Immunology.  13. 2012-12-01
  • Pre-Transplant Myeloid Dendritic Cell Deficiency Associated With Cytomegalovirus Infection and Death After Kidney Transplantation.  Transplant infectious disease.  14:618-625. 2012-12-01
  • Anti-Thymocyte Globulin (Atg) Differentially Depletes Naive and Memory T Cells and Permits Memory-Type Regulatory T Cells.  Blood.  120. 2012-11-01
  • Implementing Personalized Medicine: Development of a Cost-Effective Customized Pharmacogenetics Genotyping Array.  Clinical Pharmacology & Therapeutics.  92:437-439. 2012-10-01
  • Total Synthesis of Grassystatin A, a Probe for Cathepsin E Function.  Bioorganic & Medicinal Chemistry.  20:4774-4780. 2012-08-01
  • The Tyrphostin Agent Ag490 Prevents and Reverses Type 1 Diabetes in Nod Mice.  PLoS One.  7. 2012-05-01
  • University of Florida Clinical and Translational Science Institute: Transformation and Translation in Personalized Medicine.  Clinical and Translational Science.  4:400-402. 2011
  • Erythrocyte Membrane Omega-3 Fatty Acid Levels and Omega-3 Fatty Acid Intake Are Not Associated With Conversion To Type 1 Diabetes in Children With Islet Autoimmunity: the Diabetes Autoimmunity Study in the Young (Daisy).  Pediatric Diabetes.  12:669-675. 2011-12-01
  • Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes.  Diabetes.  60:2566-2570. 2011-10-01
  • Parvovirus B19 Infection in Hashimoto's Thyroiditis, Papillary Thyroid Carcinoma, and Anaplastic Thyroid Carcinoma.  Thyroid.  21:411-417. 2011-04-01
  • Adhesive Substrates Modulate the Activation and Stimulatory Capacity of Non-Obese Diabetic Mouse-Derived Dendritic Cells.  Acta Biomaterialia.  7:180-192. 2011-01-01
  • Multifunctional Dendritic Cell-Targeting Polymeric Microparticles Engineering New Vaccines for Type 1 Diabetes.  Human Vaccines.  7:37-44. 2011-01-01
  • Erythrocyte Membrane Fatty Acid Content in Infants Consuming Formulas Supplemented With Docosahexaenoic Acid (Dha) and Arachidonic Acid (Ara): An Observational Study.  Maternal and Child Nutrition.  6:338-346. 2010-10-01
  • The Modulation of Dendritic Cell Integrin Binding and Activation By Rgd-Peptide Density Gradient Substrates.  Biomaterials.  31:7444-7454. 2010-10-01
  • Experimental Extracorporeal Photopheresis Therapy Significantly Delays the Development of Diabetes in Non-Obese Diabetic Mice.  Clinical Immunology.  135:374-383. 2010-06-01
  • Hyper-Responsive Phenotype in Localized Aggressive Periodontitis.  Journal of Dental Research.  89:143-148. 2010-02-01
  • Experimental extracorporeal photopheresis therapy significantly delays the development of diabetes in non-obese diabetic mice..  Clinical Immunology.  135. 2010
  • Dendritic Cell Deficiency Associated With Development of Bk Viremia and Nephropathy in Renal Transplant Recipients 2010-01-01
  • A High-Throughput Microparticle Microarray Platform for Dendritic Cell-Targeting Vaccines.  Biomaterials.  30:4168-4177. 2009-09-01
  • Extracorporeal Photopheresis-Induced Immune Tolerance: a Focus On Modulation of Antigen-Presenting Cells and Induction of Regulatory T Cells By Apoptotic Cells.  Current Opinion in Organ Transplantation.  14:338-343. 2009-08-01
  • Rabbit Polyclonal Anti-Mouse Thymocyte Globulin Administration Alters Dendritic Cell Profile and Function in Nod Mice To Suppress Diabetogenic Responses.  Journal of Immunology.  182:4608-4615. 2009-04-01
  • Anti-Mouse Thymocyte Globulin Administration Alters Dendritic Cell Profile and Function in Nod Mice To Suppress Diabetogenic Responses..  American Journal of Transplantation.  9:720. 2009-01-01
  • Dendritic Cell Therapy for Prevention of Type 1 Diabetes: Role of Peptide Presentation On Immune Modulation.  Clinical Immunology.  131:S56. 2009-01-01
  • Adhesive Substrate-Modulation of Adaptive Immune Responses.  Biomaterials.  29:4736-4750. 2008-12-01
  • Comparison Between Omega-3 and Omega-6 Polyunsaturated Fatty Acid Intakes as Assessed By a Food Frequency Questionnaire and Erythrocyte Membrane Fatty Acid Composition in Young Children.  European Journal of Clinical Nutrition.  62:733-738. 2008-06-01
  • Infusion of Uvb-Treated Splenic Stromal Cells Induces Suppression of Beta Cell Antigen-Specific T Cell Responses in Nod Mice.  Journal of Autoimmunity.  30:283-292. 2008-06-01
  • Murine Antithymocyte Globulin Therapy Alters Disease Progression in Nod Mice By a Time-Dependent Induction of Immunoregulation.  Diabetes.  57:405-414. 2008-02-01
  • Adhesive substrate-modulation of adaptive immune responses..  Biomaterials.  29. 2008
  • Infusion of UVB-treated splenic stromal cells induces suppression of beta cell antigen-specific T cell responses in NOD mice..  Journal of Autoimmunity.  30. 2008
  • Apoptotic Non-Beta Cells Suppress Beta Cell Antigen-Reactive T Cells and Induce Beta Cell Antigen-Specific Regulatory T Cells Transfusion of Apoptotic Splenic Stromal Cells Prevents Type 1 Diabetes 2008-01-01
  • Dendritic cells post-maturation are reprogrammed with heightened IFN-gamma and IL-10..  Biochemical and Biophysical Research Communications.  352. 2007
  • Transfusion of apoptotic beta-cells induces immune tolerance to beta-cell antigens and prevents type 1 diabetes in NOD mice..  Diabetes.  56. 2007
  • Truncated pStat5B is associated with the Idd4 locus in NOD mice..  Biochemical and Biophysical Research Communications.  356. 2007
  • Eicosanoid imbalance in the NOD mouse is related to a dysregulation in soluble epoxide hydrolase and 15-PGDH expression..  Annals of the New York Academy of Sciences.  1079. 2006
  • In vivo transduction of thymic dendritic cells with adenovirus and its potential use in acute inflammatory diseases..  Scandinavian Journal of Immunology.  61. 2005
  • Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction..  Journal of Immunology.  175. 2005
  • Signal transduction activator of transcription 5 (STAT5) dysfunction in autoimmune monocytes and macrophages..  Journal of Autoimmunity.  24. 2005
  • The effects of renal transplantation on peripheral blood dendritic cells..  Clinical Transplantation.  19. 2005
  • IL10 resistant PGS2 expression in at-risk/Type 1 diabetic human monocytes..  Journal of Autoimmunity.  22. 2004
  • Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression?.  Pediatric Diabetes.  5. 2004
  • Fas stimulation results in selective islet infiltrate apoptosis in situ and reversal of diabetes..  Annals of the New York Academy of Sciences.  958. 2002
  • Systemic infection of mice by wild-type but not Spv- Salmonella typhimurium is enhanced by neutralization of gamma interferon and tumor necrosis factor alpha..  Infection and Immunity.  65. 1997
  • The effects of renal transplantation on circulating precursor dendritic cells..  Transplantation proceedings.  37.

• conference poster

  • Facilitating Genetic Testing for both Clinical Care and Research 2013
  • Facilitating Genetic Testing for both Clinical Care and Research 2013

principal investigator on

• Assess of Mutated Stat5b in Regulatory T Cell Development in Nod Mice  awarded by Juvenile Diabetes Research Foundation 2005 - 2006
• Assess of Mutated Stat5b in Regulatory T Cell Development in Nod Mice  awarded by Juvenile Diabetes Research Foundation 2004 - 2005
• Assess of Mutated Stat5b in Regulatory T Cell Development in Nod Mice  awarded by Juvenile Diabetes Research Foundation 2006 - 2007
• Cooperative Human Tissue Network  awarded by NIH Bethesda 2008 - 2010
• Dendritic Cells and the Prevention of Type 1 Diabetes  awarded by NIH Bethesda 2005 - 2010
• Disbursement Request for Housestaff Stipends and Fringe Benefits  awarded by US Department of Veterans Affairs 1992 - 2012
• Editorship - Laboratory Investigation  awarded by US and Canadian Academy of Pathology 2009
• Total Cancer Care: a Partnership with High Risk And/Or Diagnosed Cancer Patients for Life  awarded by H Lee Moffitt Cancer Center 2009 - 2010
• Trialnet Inflammatory Mediators Laboratory  awarded by NIH Bethesda 2008 - 2010
• Trialnet Inflammatory Mediators Laboratory  awarded by NIH Bethesda 2008
• Trialnet Inflammatory Mediators Laboratory  awarded by National Institute of Diabetes and Digestive and Kidney Diseases 2007 - 2008
• Trialnet Inflammatory Mediators Laboratory  awarded by NIH Bethesda 2006 - 2007
• UFF Chandler Stetson Professorship in Experimental Pathology  awarded by University of Florida Foundation, Inc 2010 - 2017

co-principal investigator on

• Cytokine Regulation in Sepsis/Inflammation  awarded by National Institute of General Medical Sciences 2008 - 2012
• Dendritic Cell-Targeting Microparticles for Subcellularly- Targeted Delivery of Vitamin D3, Tgf-Beta1 and Gm-Csf ....  awarded by NIH Bethesda 2011 - 2012
• Immune Function and the Progression to Type 1 Diabetes  awarded by National Institute of Allergy and Infectious Diseases 2007 - 2013
• Michigan Institute for Clinical and Health Research (Michr)  awarded by National Center for Research Resources 2011 - 2012
• Neutrophil Apoptosis and Neonatal Inflammation  awarded by NIH Bethesda 2005 - 2006
• Project Ii: Immune Function in Low Risk Genotypes in Idd  awarded by National Institute of Allergy and Infectious Diseases 2001 - 2007
• Shands Housestaff Education Agreement  awarded by Shands Teaching Hospital Housestaff 2009 - 2012
• Shands Housestaff Education Agreement  awarded by Shands Teaching Hospital Housestaff 2008 - 2010
• Targeted Interleukin-10 Gene Therapy in Sepsis Syndromes  awarded by National Institute of General Medical Sciences 2005 - 2009
• Trialnet: University of Florida Clinical Center and Network  awarded by National Institute of Diabetes and Digestive and Kidney Diseases 2009 - 2014
• Whole Transcriptome Sequencing of Non-Small-Cell Lung Cancer (Nsclc)  awarded by State University System Of Florida Board Of Governors 2006 - 2015

teaching activities

• BME7979 Fall 2008 7211 BME7979 Fall 2008 7211
• BME7979 Spring 2009 6282 BME7979 Spring 2009 6282
• BME7979 Summer 2009 7234 BME7979 Summer 2009 7234
• BME7980 Fall 2008 7212 BME7980 Fall 2008 7212
• BME7980 Fall 2009 7212 BME7980 Fall 2009 7212
• BME7980 Fall 2010 7212 BME7980 Fall 2010 7212
• BME7980 Fall 2011 2951 BME7980 Fall 2011 2951
• BME7980 Spring 2009 6465 BME7980 Spring 2009 6465
• BME7980 Spring 2010 6465 BME7980 Spring 2010 6465
• BME7980 Spring 2011 6465 BME7980 Spring 2011 6465
• BME7980 Summer 2009 7235 BME7980 Summer 2009 7235
• BME7980 Summer 2010 7235 BME7980 Summer 2010 7235
• BME7980 Summer 2011 7235 BME7980 Summer 2011 7235
• BMS4905 Fall 2011 9242 BMS4905 Fall 2011 9242
• BMS6601C Fall 2008 8568 BMS6601C Fall 2008 8568
• BMS6602C Spring 2010 8506 BMS6602C Spring 2010 8506
• BMS6602C Spring 2011 8506 BMS6602C Spring 2011 8506
• GMS6033 Fall 2009 4771 GMS6033 Fall 2009 4771
• GMS6033 Fall 2010 4771 GMS6033 Fall 2010 4771
• GMS6090 Fall 2008 0110 GMS6090 Fall 2008 0110
• GMS6090 Fall 2010 0110 GMS6090 Fall 2010 0110
• GMS6090 Spring 2009 4876 GMS6090 Spring 2009 4876
• GMS6090 Spring 2009 976 GMS6090 Spring 2009 976
• GMS6140 Fall 2008 4782 GMS6140 Fall 2008 4782
• GMS6140 Fall 2009 4782 GMS6140 Fall 2009 4782
• GMS6140 Fall 2010 4782 GMS6140 Fall 2010 4782
• GMS6382 Fall 2011 1461 GMS6382 Fall 2011 1461
• GMS6382 Spring 2009 3921 GMS6382 Spring 2009 3921
• GMS6382 Spring 2010 3921 GMS6382 Spring 2010 3921
• GMS7979 Fall 2009 0234 GMS7979 Fall 2009 0234
• GMS7979 Fall 2010 0234 GMS7979 Fall 2010 0234
• GMS7979 Fall 2011 0234 GMS7979 Fall 2011 0234
• GMS7979 Spring 2010 1927 GMS7979 Spring 2010 1927
• GMS7979 Spring 2011 1927 GMS7979 Spring 2011 1927
• GMS7979 Summer 2009 8121 GMS7979 Summer 2009 8121
• GMS7979 Summer 2010 8121 GMS7979 Summer 2010 8121
• GMS7980 Fall 2008 0244 GMS7980 Fall 2008 0244
• GMS7980 Fall 2009 0244 GMS7980 Fall 2009 0244
• GMS7980 Fall 2011 0244 GMS7980 Fall 2011 0244
• GMS7980 Spring 2009 2753 GMS7980 Spring 2009 2753
• GMS7980 Spring 2010 2753 GMS7980 Spring 2010 2753
• GMS7980 Spring 2011 2753 GMS7980 Spring 2011 2753
• GMS7980 Summer 2009 8122 GMS7980 Summer 2009 8122
• GMS7980 Summer 2010 8122 GMS7980 Summer 2010 8122
• GMS7980 Summer 2011 8122 GMS7980 Summer 2011 8122
• IDH4917 Fall 2008 3468 IDH4917 Fall 2008 3468
• IDH4917 Spring 2009 2151 IDH4917 Spring 2009 2151
• MCB4905 Fall 2009 8463 MCB4905 Fall 2009 8463
• MCB4905 Spring 2009 8432 MCB4905 Spring 2009 8432
• MCB4905 Spring 2010 8432 MCB4905 Spring 2010 8432
• ZOO4905 Spring 2009 7681 ZOO4905 Spring 2009 7681

education

• M.D., University at Buffalo 1979

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