Differential Reactivity To Impdh2 By Anti-Rods/Rings Autoantibodies and Unresponsiveness To Pegylated Interferon-Alpha/Ribavirin Therapy in Us and Italian Hcv Patients Academic Article uri icon


  • Autoantibodies to cytoplasmic structures called rods and rings (RR) are primarily specific to patients with hepatitis C virus (HCV) infection treated with pegylated interferon-alpha/ribavirin (IFN/R). Our aim is to examine anti-RR antibodies specificity and correlation with the response to IFN/R therapy in two independent cohorts (US and Italy) of HCV patients.

publication date

  • 2013-02-01