Ishov, Alexander M

Ishov, Alexander M

Associate Professor

Positions

Associate Professor, Anatomy and Cell Biology , College of Medicine 2003 -
Faculty, Anatomy and Cell Biology , College of Medicine 2004 -
Assistant Professor, Anatomy and Cell Biology , College of Medicine 2003 - 2010
Senior Scientist, The Wistar Institute (Philadelphia, PA) 2003
Staff Scientist, The Wistar Institute (Philadelphia, PA) 2001 - 2002
Director of the Microscopy and Histotechnology Core Facility, The Wistar Institute (Philadelphia, PA) 1999 - 2001
Staff Scientist, The Wistar Institute (Philadelphia, PA) 1997 - 1999
Postdoctoral Training, The Wistar Institute (Philadelphia, PA) 1994 - 1997

research areas

has course role

home department

Anatomy and Cell Biology Academic Department

selected publications

academic article
- Cenp-B Protects Centromere Chromatin Integrity By Facilitating Histone Deposition Via the H3.3-Specific Chaperone Daxx. Epigenetics & Chromatin. 10. 2017
- Cenp-B Protects Centromere Chromatin Integrity By Facilitating Histone Deposition Via the H3.3-Specific Chaperone Daxx. Epigenetics & Chromatin. 10. 2017
- Inhibitor of H3K27 Demethylase Jmjd3/Utx Gsk-J4 Is a Potential Therapeutic Option for Castration Resistant Prostate Cancer. Oncotarget. 8:62131-62142. 2017
- Inhibitor of H3K27 Demethylase Jmjd3/Utx Gsk-J4 Is a Potential Therapeutic Option for Castration Resistant Prostate Cancer. Oncotarget. 8:62131-62142. 2017
- The Histone Chaperone Daxx Maintains the Structural Organization of Heterochromatin Domains 2015
- Usp7 Protects Genomic Stability By Regulating Bub3. Oncotarget. 5:3728-3742. 2014-06-01
- Targeting Mitotic Exit With Hyperthermia Or Apc/C Inhibition To Increase Paclitaxel Efficacy. Cell Cycle. 12:2598-2607. 2013-08-01
- Function of Daxx/Atrx Complex At Centromeric and Pericentromeric Heterochromatin. Febs Journal. 280:23. 2013-07-01
- Usp7 and Daxx Regulate Mitosis Progression and Taxane Sensitivity By Affecting Stability of Aurora-a Kinase. Cell Death and Differentiation. 20:721-731. 2013-05-01
- Dualistic Function of Daxx At Centromeric and Pericentromeric Heterochromatin in Normal and Stress Conditions. Nucleus. 3:276-285. 2012-05-01
- Regulation of Mitosis and Taxane Response By Daxx and Rassf1. Oncogene. 31:13-26. 2012-01-01
- Tandemly Repeated Dna Families in the Mouse Genome. Bmc Genomics. 12. 2011-10-01
- The Herpes Simplex Virus Immediate-Early Ubiquitin Ligase Icp0 Induces Degradation of the Icp0 Repressor Protein E2Fbp1. Journal Of Virology. 85:3356-3366. 2011-04-01
- Structural Characterization of the Daxx N-Terminal Helical Bundle Domain and Its Complex With Rassf1C. Structure. 18:1642-1653. 2010-12-01
- Daxx Is a Predominately Nuclear Protein That Does Not Translocate To the Cytoplasm in Response To Cell Stress. Cell Cycle. 8:1544-1551. 2009-05-01
- Pml Nbs (Nd10) and Daxx: From Nuclear Structure To Protein Function 2008-05-01
- Regulation of C-Met Expression By Transcription Repressor Daxx. Oncogene. 27:2177-2186. 2008-04-01

principal investigator on

Histone Variant H3.3 and Kshv Lana in the Pathogenesis of Oral Kaposi's Sarcoma awarded by National Institute of Dental and Craniofacial Research 2014 - 2016
Gap Funding for Breast Cancer Treatment Research awarded by Florida Clinical Practice Association 2014 - 2015
Structure and Function of the Human Beta-Globulin Locus Control Region (Supplement for Joeva Barrow) awarded by National Institute of Diabetes and Digestive and Kidney Diseases 2010 - 2014
Functionof Daxx in Mitosis That Determines Paclitaxel Sensitivity in Breast Cancer awarded by National Cancer Institute 2007 - 2013
Novel Therapeutic Strategy to Overcome Taxane Resistance in Breast Cancer awarded by Shula Foundation 2011 - 2013
UF Medical Guild awarded by University of Florida Medical Guild 2010 - 2011
Tumor Suppression Function of Daxx in Tobaco-Smoke-Mediated Cmet-Dependent Breast Malignancy awarded by Florida Department of Health J and E King Biomedical Research Program 2005 - 2008
Function of Daxx in Mitosis That Determines Paclitaxel Sensitivity in Breast Cancer awarded by Florida Department of Health J and E King Biomedical Research Program 2007
Implication of Potential Tumor Suppression Function of Daxx in C-Met Dependent Lung Malignancy awarded by Flight Attendant Medical Research Institute 2004 - 2007

investigator on

UF Health Cancer Center Bridge Seed Grant awarded by UF Health Shands Hospital 2015

teaching activities

ALS4905 Spring 2011 3652 ALS4905 Spring 2011 3652
CHM4905 Fall 2011 9471 CHM4905 Fall 2011 9471
CHM4905 Summer 2011 7398 CHM4905 Summer 2011 7398
GMS6001 Fall 2009 0086 GMS6001 Fall 2009 0086
GMS6001 Fall 2010 0086 GMS6001 Fall 2010 0086
GMS6061 Spring 2009 4296 GMS6061 Spring 2009 4296
GMS6062 Spring 2010 0169 GMS6062 Spring 2010 0169
GMS6062 Spring 2011 0169 GMS6062 Spring 2011 0169
GMS6062 Spring 2012 1F05
GMS6064 Spring 2009 4287 GMS6064 Spring 2009 4287
GMS6064 Spring 2011 6258 GMS6064 Spring 2011 6258
GMS6090 Fall 2008 0110 GMS6090 Fall 2008 0110
GMS6090 Fall 2010 0110 GMS6090 Fall 2010 0110
GMS6090 Spring 2009 976 GMS6090 Spring 2009 976
GMS6090 Spring 2011 4876 GMS6090 Spring 2011 4876
GMS6421 Fall 2009 2110 GMS6421 Fall 2009 2110
GMS6692 Fall 2010 2075 GMS6692 Fall 2010 2075
GMS6692 Fall 2011 2075 GMS6692 Fall 2011 2075
GMS6692 Spring 2010 5142 GMS6692 Spring 2010 5142
GMS6692 Spring 2011 5142 GMS6692 Spring 2011 5142
GMS7979 Fall 2008 0234 GMS7979 Fall 2008 0234
GMS7979 Fall 2009 0234 GMS7979 Fall 2009 0234
GMS7979 Fall 2010 0234 GMS7979 Fall 2010 0234
GMS7979 Fall 2011 0234 GMS7979 Fall 2011 0234
GMS7979 Spring 2009 1927 GMS7979 Spring 2009 1927
GMS7979 Spring 2010 1927 GMS7979 Spring 2010 1927
GMS7979 Spring 2011 1927 GMS7979 Spring 2011 1927
GMS7979 Summer 2009 8121 GMS7979 Summer 2009 8121
GMS7979 Summer 2010 8121 GMS7979 Summer 2010 8121
GMS7979 Summer 2011 8121 GMS7979 Summer 2011 8121
GMS7980 Fall 2008 0244 GMS7980 Fall 2008 0244
GMS7980 Fall 2009 0244 GMS7980 Fall 2009 0244
GMS7980 Fall 2010 0244 GMS7980 Fall 2010 0244
GMS7980 Fall 2011 0244 GMS7980 Fall 2011 0244
GMS7980 Spring 2009 2753 GMS7980 Spring 2009 2753
GMS7980 Spring 2010 2753 GMS7980 Spring 2010 2753
GMS7980 Spring 2011 2753 GMS7980 Spring 2011 2753
GMS7980 Summer 2009 8122 GMS7980 Summer 2009 8122
GMS7980 Summer 2010 8122 GMS7980 Summer 2010 8122
GMS7980 Summer 2011 8122 GMS7980 Summer 2011 8122

professional service activities

Graduate Advisory Committee for Richard Johns External Member 2009 -

education and training

Ph.D. in Cellular and Molecular Biology, Institute of Cytology (Russian Academy of Science) 1994
M.S. in Genetics, State Pedagogical University 1989
B.S. in Biology, State Pedagogical University 1987

full name

Alexander M Ishov

primary email

ishov@ufl.edu

phone

(352) 273-8202

Publications in VIVO

Co-author Network

Co-investigator Network

Contact Info

ishov@ufl.edu

(352) 273-8202