selected publications academic article Microscopic Polyangiitis With Diffuse Alveolar Hemorrhage and Glomerulonephritis Complicating Acute Influenza Infection. Jcr-Journal of Clinical Rheumatology. S618-S619. 2021 Myxomavirus serpin alters macrophage function and prevents diffuse alveolar hemorrhage in pristane-induced lupus. Clinical Immunology. 108764. 2021 Reply to comment on: Nrf2 regulates interferon receptor expression and alters macrophage polarization in lupus. Arthritis & Rheumatology. 2020 Nrf2 regulates interferon receptor expression and alters macrophage polarization in lupus. Arthritis & Rheumatology. 2020 High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. JCI Insight. 2019 Differential responsiveness of monocyte and macrophage subsets to interferon. Arthritis & Rheumatology. 2019 Irisin Attenuates Neuroinflammation and Prevents the Memory and Cognitive Deterioration in Streptozotocin-Induced Diabetic Mice. Mediators of Inflammation. 2019 The Association between Depression and Type 1 Diabetes Mellitus: Inflammatory Cytokines as Ferrymen in between?. Mediators of Inflammation. 2019 Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages. Frontiers in Immunology. 135. 2018 A Novel Subset of Anti-Inflammatory Cd138(+) Macrophages Is Deficient in Mice With Experimental Lupus. Journal of Immunology. 199:1261-1274. 2017 Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus. Arthritis & Rheumatology. 69:1280-1293. 2017 A Novel Mechanism for Generating the Interferon Signature in Lupus Opsonization of Dead Cells By Complement and Igm. Arthritis & Rheumatology. 68:2917-2928. 2016 "Lupoid Hepatitis" in SLE Patients and Mice With Experimental Lupus 2016 Lamotrigine Reduces Inflammatory Response and Ameliorates Executive Function Deterioration in An Alzheimer'S-Like Mouse Model 2016 Maintenance of Autoantibody Production in Pristane-Induced Murine Lupus. Arthritis Research & Therapy. 17. 2015 Mechanisms of Autoantibody Production in Systemic Lupus Erythematosus. Frontiers in Immunology. 6. 2015-05-01 Stat3 Signaling Contributes To the High Effector Activities of Interleukin-15-Derived Dendritic Cells. Immunology and Cell Biology. 93:461-471. 2015-05-01 Animal Models of Interferon Signature Positive Lupus. Frontiers in Immunology. 291. 2015 Mechanisms of Tumor Necrosis Factor Alpha Antagonist-Induced Lupus in a Murine Model. Arthritis & Rheumatology. 67:225-237. 2015-01-01 Expression of Recombinant Human Il-4 in Pichia Pastoris and Relationship Between Its Glycosylation and Biological Activity. Protein Expression and Purification. 96:1-7. 2014-04-01 Toll-like receptor 7-stimulated tumor necrosis factor α causes bone marrow damage in systemic lupus erythematosus. Arthritis & Rheumatology. 2014 Cd40 Exon 8 Deficiency Causes a Novel Form of Immunodeficiency With Hyper-Igm. Journal of Immunology. 190. 2013-05-01 Novel Autoantigens in Type 1 Diabetes. American Journal of Translational Research. 5:379-392. 2013-01-01 Novel Detection of Pancreatic and Duodenal Homeobox 1 Autoantibodies (Paa) in Human Sera Using Luciferase Immunoprecipitation Systems (Lips) Assay. International Journal of Clinical and Experimental Pathology. 6:1202-1210. 2013-01-01 Characterization and Immunotherapeutic Implication of a Novel Cerebro-Spinal Fluid-Derived Alk-Positive Anaplastic Large Cell Lymphoma Cell Line. Blood. 120. 2012-11-01 Pleiotropic Ifn-Dependent and -Independent Effects of Irf5 On the Pathogenesis of Experimental Lupus. Journal of Immunology. 188:4113-4121. 2012-04-01 The Enzymatic Activity of Human Aldehyde Dehydrogenases 1A2 and 2 (Aldh1A2 and Aldh2) Is Detected By Aldefluor, Inhibited By Diethylaminobenzaldehyde and Has Significant Effects On Cell Proliferation and Drug Resistance. Chemico-Biological Interactions. 195:52-60. 2012-01-01 Human Antigen-Specific Regulatory T Cells Generated By T Cell Receptor Gene Transfer. PLoS One. 5. 2010-07-01 Lentiviral Calnexin-Modified Dendritic Cells Promote Expansion of High-Avidity Effector T Cells With Central Memory Phenotype. Immunology. 128:43-57. 2009-09-01 Phenotype and Functional Evaluation of Ex Vivo Generated Antigen-Specific Immune Effector Cells With Potential for Therapeutic Applications. Journal of Hematology & Oncology. 2. 2009-08-01 Phenotype and Functional Evaluation of Ex Vivo Generated Antigen-Specific Immune Effector Cells With Potential for Therapeutic Applications. Journal of Hematology & Oncology. 2. 2009-08-01 Immunity of lentiviral vector-modified dendritic cells. Methods in Molecular Biology. 2009 Overcoming Immune Tolerance Against Multiple Myeloma With Lentiviral Calnexin-Engineered Dendritic Cells. Molecular Therapy. 16:269-279. 2008-02-01
other research activities Immortalization of MM cells isolated from bone marrow of patients Researcher Monitoring regulatory T cells in MM patients before and after chemotherapy Researcher
education and training Ph.D. in Immunology, Department of Immunology (Peking University) 2001 M.S. in Immunology, Department of Immunology (Peking University) 1998 B.S. in Preventive Medicine, China Medical University , Department of Preventive Medicine 1995
awards and honors 1999-2000 Guanghua Scholarship, Beijing Medial University 1990-1995 Undergraduate Scholarship, China Medical University
mailing address 2033 Mowry RoadRoom 105P.O. Box 103610, Department of Molecular Genetics and Microbiology Gainesville, Florida 32610 United States